South Eleuthera (a prime area) encompasses the settlements of Greencastle, Wemyss Bight, Waterford, Deep Creek, The Village, Millars, Delancey Town, and Bannerman Town. The largest town in the region is Rock Sound.

There is very little tourist activity in South Eleuthera, being only a short stopover point for cruise lines.

The few attractions on the island include the Cotton Bay Club and Golf Course, the snorkeling and sunbathing spot of Jack’s Bay, and the Island School on the Cape Peninsula, which specializes in courses on the Caribbean ecosystem.

There are a few affluent resort communities in South Eleuthera. Powell Point consists of townhouses, beach villas, estate homes, and a deep water marina. The 1,500-acre Cotton Bay has a pink sand beach, a boutique hotel, a clubhouse, estate lots and villas. Windermere Island is a gated private island with a pink sand beach stretching for much of the length of the island along its Atlantic side. In 2006, the northern part of the island was earmarked for residential development. A favourite resort of the British Royal Family, it was at Windermere where the scandalous 1982 paparazzi photo of a pregnant Princess Diana in a bikini was taken.

These upmarket communities are not the only options for property buyers. Savannah Sound offers 4-acre waterfront lots with 100 feet of frontage. However, there are no utilities, so homeowners have to bring their own generators and cellphones. South of Savannah Sound is Atlantic Cove, a 2-mile-long Atlantic beach with an offshore reef system. Next is Winding Bay Beach, a scenic horseshoe-shaped beach protected by a reef. Two-acre lots with 100 to 200 feet of beach frontage are offered here. North of Windermere Island is the 3-mile-long Double Bay, one of the oldest beachfront estate developments in the area.

Families are drawn to Ten Bay Beach on the Caribbean side of South Eleuthera because the waters are calm and shallow.