The Amazonas state, as its name suggests lies in the Amazon region. The Amazon covers most of South America and is the greenest place in the world, which means the Amazonas has an abundance of rainforests, savannas and rivers, the long and wide Orinoco River among them.

The region teems with wildlife: pumas, jaguars, monkeys, bears, foxes, snakes, turtles, toucans, river dolphins and electric eels. The dense jungle possesses about 8,000 varieties of plants, 7,000 of which are indigenous to the area. The state has four national parks—Yapacana, Serrania La Neblina, Parima Tapirapeco and Duida Marahuaca. The Sipapo forest reserve and the Alto Orinoco-Casiquiare biosphere reserve protect wildlife and vegetation as well.

The Amazonas is one of the least populated states in the country. It is the home of 20 distinct indigenous groups, including the semi-nomadic and most isolated tribe, the Yanomami. In the economic sense, this remote region is poor, and most communities rely on subsistence fishing. The cultivation of conucos, or small plots of lands, is also limited, with scarce production of yucca, cambur, banana, corn and cane. Commercial fishing is concentrated in the state capital of Puerto Ayacucho, but is restricted.